Henry de Vries
STI Outpatient Clinic, Cluster Infectious Diseases, Health Service Amsterdam, Amsterdam, The Netherlands; Amsterdam UMC, University of Amsterdam, Department of Dermatology, Amsterdam Institute for Infection and Immunity (AI&II), Meibergdreef 9, Amsterdam, The Netherlands
Lymphogranuloma venereum (LGV) is endemic among European men who have sex with men (MSM) since 2003. It is a relatively common cause of proctitis, but rarely causes genital or oro-pharyngeal infections. In this presentation new and important issues in the 2019 version will be discussed.
- LGV continues to be endemic among European men who have sex with men (MSM) since 2003.
- LGV infections in heterosexuals are extremely rare in Europe, and there is no evidence of transmission of LGV in the European heterosexual population.
Aetiology and transmission
- Chlamydia trachomatis serovars/genovars L2b and L2 are the causative strains in the majority of cases in Europe.
- Among MSM, about 25% of the anorectal LGV infections are asymptomatic.
- Genital infections among MSM are rare; the ratio of genital vs. anorectal LGV infections is 1 in 15.
- To diagnose LGV, a sample tested C. trachomatis positive with a commercial nucleic acid amplification test (NAAT) platform should be confirmed with an LGV discriminatory NAAT.
- Doxycycline 100 mg twice a day orally for 21 days is the recommended treatment for LGV.
- This same treatment is recommended also in asymptomatic patients and contacts of LGV patients. If another regimen is used a test of cure (TOC) must be performed.
34 IUSTI Congress - European Congres on Sexually transmitted Infections and HIV/AIDS
TAMING THE TIDE of STIs & HIV
Bucharest, September 3-5,